Lon Castle


Lab and Specialty Drug Services

eviCore healthcare

Dr. Castle is responsible for the clinical performance of the Laboratory and Specialty Drug programs at eviCore healthcare, a wholly-owned subsidiary of Cigna. He has been working in the genomic and molecular diagnostic field for over a decade, both designing initiatives that support the advancement of precision medicine as well as managing programs that ensure these tests are used appropriately.

Previously, Dr. Castle worked as the Medical Director for Managed Care at CardioDx where he was responsible for discussing the science of their gene expression test to detect coronary artery disease to payers. Part of that included helping to design projects that demonstrated the clinical value of the test to payers. As part of the Medical Affairs team, Dr. Castle was also involved in the clinical and health economic study designs.

Before CardioDx, Dr. Castle was employed at Medco Health Solutions (now Express Scripts) as the Senior Director for Clinical Innovation. During his 12 years there he worked on numerous projects, including the initial development of the company’s personalized medicine testing programs, demonstration projects with pharmaceutical manufacturers to establish the value of genetic markers for novel medications and publication of the organization’s annual Drug Trend Report. 

Dr. Castle received his undergraduate degrees in Biology and English from Bucknell University in Lewisburg, PA. He received his medical degree from the Medical College of Ohio in Toledo. He completed his residency in Family and Community Medicine at the Medical Center of Delaware in Wilmington and his Sports Medicine fellowship at The Ohio State University in Columbus. Dr. Castle practiced sports medicine for over a decade at the Baylor College of Medicine and the Baylor Sports Medicine Institute in Houston, TX, serving as team physician for numerous professional, college and high school sports teams.